Publications (pdf)            back                Tim Hubin          tim.hubin@swosu.edu

“Probing the limits of tetraazamacrocycle-glyoxal condensates as bidentate ligands for copper(II): homocyclam, pyruvic aldehyde, and butanedione condensate analogues”  Won, P. D.; Funwie, N. L.; Birdsong, O. C.; Yilmaz Obali, A.; Burke, B. P.; McRobbie, G.; Greenman, P.; Prior, T. J.; Archibald, S. J.; Hubin, T. J.  Eur. J. Inorg. Chem., 2015, 4678-4688.

 

“Dichloro(4,11-dimethyl-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane)iron(III) hexafluorophosphate”  Funwie, N. L.; Cain, A. N.; Fanning, B. Z.; Hageman, S. A.; Mullens, M.; Roberts, T. K.; Turner, D. J.; Valdez, C. N.; Vaughan, R. W.; Ermias, H. G.; Silversides, J. D.; Archibald, S. J.; Hubin, T. J.; Prior, T. J. Acta Cryst E, 2015, E71, 1073-1076.

 

“Synthesis, structural studies, and oxidation catalysis of the manganese(II), iron(II), and copper(II) complexes of a 2-pyridylmethyl pendant armed side-bridged cyclam” Shircliff, A. D.; Wilson, K. R.; Cannon-Smith, D. J.; Jones, D. G.; Zhang, Z.; Chen, Z.; Yin, G.; Prior, T. J.; Hubin, T. J. Inorg. Chem. Commun., 2015, 59. 71-75.

 

“Synthesis, structural studies, kinetic stability, and oxidation catalysis of the late first row transition metal complexes of 4,10-dimethyl-1,4,7,10-tetraazabicyclo[6.5.2]pentadecane” Matz, D. L.; Jones, D. G.; Roewe, K. D.; Gorbet, M.-J.; Zhang, Z.; Chen, Z.; Prior, T. J.; Archibald, S. J; Yin, G.;. Hubin, T. J. Dalton Trans. 2015, 44, 12210-12224.

 

“IL-24 prevents lung cancer cell migration and invasion by disrupting the SDF-1α/CXCR4 signaling axis”

Panneerselvam, J.; Jin, J.; Shanker, M.; Lauderdale, J.; Bates, J.; Wang, Q.; Khan, A.; Hubin, T. J.; Archibald, S. J.; Ramesh. R. PLOS One, 2015, 10, 0122439.

 

“Synthesis, structural studies, and oxidation catalysis of the late first row transition metal complexes of a 2-pyridylmethyl pendant armed ethylene cross-bridged cyclam” Jones, D. G.; Wilson, K. R.; Cannon-Smith, D. J.; Shircliff, A. D.; Zhang, Z.; Chen, Z.; Yin, G.; Prior, T. J.; Hubin, T. J.  Inorg. Chem., 2015, 54, 2221-2234.

 

“Influences of Calcium(II) and Chloride on the Oxidative Reactivity of a Manganese(II) Complex of a Cross-bridged Cyclen Ligand” Zhang, Z.; Coats, K. L.; Chen, Z.; Hubin, T. J.; Yin, G. Inorg. Chem., 2014, 53, 11937-11947.

 

“Determination of Log P Values of New Cyclen Based Antimalarial Drug Leads Using RP-HPLC” Rudraraju, A. V.; Amoyaw, P. N. A.; Hubin, T. J.; Khan, M. O. F. Pharmazie, 2014, 69, 655-662.

 

“Synthesis of Novel Tetraazamacrocyclic Bisquinoline Derivatives as Antimalarial Agents” Amoyaw, P. A.; Pham, K.; McClain, J. M.; Cain, A. N.; Hubin, T. J.; Khan, M. O. F. Current Organic Synthesis, 2014, 11, 916, 921.

 

“Crystal structures of two cross-bridged chromium (III) tetraazamacrocycles” Prior, T. J.; Maples, D. L.; Maples, R. D.; Hoffert, W. A.; Parsell, T. H.; Silversides, J. D.; Archibald, S. J.; Hubin, T. J. Acta Cryst., 2014, E70, 148-152.

 

“Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands” Hubin, T. J.; Amoyaw, P. N.; Roewe, K. D.; Simpson, N. C.; Maples, R. D.; Carder Freeman, T. N.; Cain, A. N.; Le, J. G.; Archibald, S. J.; Khan, S. I.; Tekwani, B. L.; Khan, M. O. F.,  Bioorganic & Medicinal Chemistry, 2014, 22, 3239-3244.

 

“Copper (I) and Copper(II) complexes with pyrazine-containing pyridylalkylamide ligands N-(pyridin-2-ylmethyl)pyrazine-2-carboxamide and N-(2-(pyridin-2-yl)ethyl)pyrazine-2-carboxamide” Houser, R. P.; Wang, Z.; Powell, D. R.; Hubin, T. J., J. Coord. Chem., 2013, 66, 4080-4092.

 

“CXCR4 chemokine receptor antagonists: nickel(II) complexes of configurationally restricted macrocycles” Smith, R.; Huskens, D.; Daelemans, D.; Mewis, R. E.; Garcia, C. D.; Cain, A. N.; Carder Freeman, T. N.; Pannecouque, C.; De Clercq, E.; Schols, D.; Hubin, T. J.; Archibald, S. J. Dalton Trans., 2012, 41, 11369-11377.

“Preparations and applications of synthetic linked azamacrocycle ligands and complexes” Timmons, J. C.; Hubin, T. J. Coord. Chem. Rev. 2010, 254, 1661-1685.

“Improving target residence time for metallodrugs by optimised coordination chemistry: fixed geometry CXCR4 chemokine receptor antagonists with improved anti-HIV properties” Khan, A.; Nicholson, G.; Greenman, J.; Madden, L.; McRobbie, G.; Pannecouque, C.; De Clercq, E.; Silversides, J. D.; Ullom, R.; Maples, D. L.; Maples, R. D.; Hubin, T. J.; Archibald, S. J. J. Am. Chem. Soc. 2009, 131, 3416-3417.

“Synthesis and Characterization of the chromium(III) complexes of ethylene cross-bridged cyclam and cyclen ligands” Maples, D. L.; Maples, R. D.; Hoffert, W. A.; Parsell, T. H.; van Asselt, A.; Silversides, J. D.; Archibald, S. J.; Hubin, T. J. Inorg. Chim. Acta 2009, 362, 2084-2088.

“The design and synthesis of pyrazine amide ligands suitable for the ‘‘tiles’’ approach to molecular weaving with octahedral metal ions” Cockriel, D.; McClain, J. M.; Patel, K. C.; Ullom, R.; Hasley, T. R.; Archibald, S. J.; Hubin, T. J. Inorg. Chem. Commun. 2008, 11, 1-4.

“Configurationally-restricted bismacrocyclic CXCR4 receptor antagonists” Valks, G. C.; McRobbie, G.; Lewis, E. A.; Hubin, T. J.; Hunter, T. M.; Sadler, P. J.; Pannecouque, C.; De Clerq, E.; Archibald, S. J.; J. Med. Chem., 2006, 49, 6162-6165.

“Dichloro(4,10-dimethyl-1,4,7,10-tetraazabicyclo[5.5.2]tetradecane)-iron(III) hexafluorophosphate” McClain, J. M.; Maples, D. L.; Maples, R. D.; Matz, D. L.; Harris, S. M.; Nelson, A. D.; Silversides, J. D.; Archibald, A.S. A.; Hubin, T. J. Acta Cryst. C, 2006, C62, m553.

“Configurationally restricted bis-azamacrocycles: chemokine receptor antagonists” Khan A.; McRobbie G.; Madden L. A.; Empson C. J.; Bridgeman A. J.; Ullom R.; Hubin T. J.; Greenman J.; Archibald S. J. Immunology, 2005, 116, 75.

“Rigidity extremes in coordination chemistry: a fine energetic balance in the isolation of a trapped ligand inversion intermediate” May, C. M.; Archibald, S. J.; Bridgeman, A. J.; Empson, C. J.; Hubin, T. J. J. Chem. Soc., Chem. Commun., 2004, 1880.

“Synthesis and characterization of the cobalt(III) complexes of two pendant-arm cross-bridged cyclams” Lichty, J.; Allen, S. M.; Grillo, A. I.; Archibald, S. J.; Hubin, T. J. Inorg. Chim. Acta, 2004, 357, 615.

“Synthesis and coordination chemistry of topologically constrained azamacrocycles” Hubin, T. J. Coord. Chem. Rev., 2003, 241, 27.

“Synthesis, structure, and stability in acid of copper(II) and zinc(II) complexes of cross-bridged tetraazamacrocycles” Hubin, T. J.; Alcock, N. W.; Morton, M. D.; Busch, D. H. Inorg. Chim. Acta, 2003, 348, 33.

“Synthesis and X-ray crystal structures of iron(II) and manganese(II) complexes of unsubstituted and benzyl substituted cross-bridged tetraazamacrocycles” Hubin, T. J.; McCormick, J. M.; Collinson, S. R.; Alcock, N. W.; Clase, H. J.; Busch, D. H. Inorg. Chim. Acta, 2003, 346, 76. 

“Synthesis and X-ray crystal structure determination of the first copper(II) complexes of tetraazamacrocycle-glyoxal condensates” Hubin, T. J.; Alcock, N. W.; Busch, D. H. Inorg. Chem., 2002, 41, 7006.

“Synthesis, characterization, and X-ray crystal structures of cobalt(II) and cobalt(III) complexes of four topologically constrained tetraazamacrocycles” Hubin, T. J.; Alcock, N. W.; Clase, H. J.; Seib, L.; Busch, D. H. Inorg. Chim. Acta, 2002, 337, 91.

“Potentiometric titrations and nickel(II) complexes of four topologically constrained tetraazamacrocycles” Hubin, T. J.; Alcock, N. W.; Clase, H. J.; Busch, D. H. Supramol. Chem., 2001, 13, 261.

“Synthesis and characterization of the novel rigid ligand 5,8-dimethyl-1,5,8,12-tetraazabicyclo[10.3.2]heptadecane and its complexation chemistry with Fe(II) and Mn(II) ions” Collinson, S. R.; Hubin, T. J.; Alcock, N. W.; Busch, D. H. J. Coord. Chem., 2001, 52, 317.

trans-Dioxocyclam (1,4,8,11-tetraazacyclotetradecane-2,9-dione) dihydrate and its Ni(II) complex” Hubin, T. J.; Tyryshkin, N.; Alcock, N. W; Busch, D. H. Acta Cryst. C, 2001, 57, 359.

“Topologically constrained manganese(III) and iron(III) complexes of two cross-bridged tetraazamacrocycles” Hubin, T. J.; McCormick, J. M.; Alcock, N. W.; Busch, D. H. Inorg. Chem., 2001, 40, 435.

“Template routes to interlocked molecular structures and orderly molecular entanglements” Hubin, T. J.; Busch, D. H. Coord. Chem. Rev., 2000, 200, 5.

“New iron(II) and manganese(II) complexes of two ultra-rigid, cross-bridged tetraazamacrocycles for catalysis and biomimicry” Hubin, T. J.; McCormick, J. M.; Collinson, S. R.; Perkins, C. M.; Alcock, N. W.; Kahol, P. K.; Raghunathan, A.; Busch, D. H. J. Am. Chem. Soc., 2000, 122, 2512.

“Cu(I) and Cu(II) complexes of an ethylene cross-bridged cyclam” Hubin, T. J.; Alcock, N. W.; Busch, D. H., Acta Cryst. C, 2000, 56, 37.

“A cyclam-like macrocycle side-bridged by a propyl chain” Hubin, T. J.; Alcock, N. W.; Busch, D. H. Acta Cryst. C, 1999, 55, 2188.  

“An o-xylyl cross-bridged 5,12-dioxocyclam” Hubin, T. J.; Tyryshkyn, N.; Alcock, N. W.; Busch, D. H. Acta Cryst. C, 1999, 55, 1888.  

“Crystallographic characterization of stepwise changes in ligand conformations as their internal topology changes, and two novel cross-bridged tetraazamacrocycle copper(II) complexes” Hubin, T. J.; McCormick, J. M.; Alcock, N. W.; Clase, H. J.; Busch, D. H. Inorg. Chem., 1999, 38, 4435.

“A complex containing copper(I) linearly coordinated by two tetracyclic tetraamines” Hubin, T. J.; Alcock, N. W.; Clase, H. J.; Busch, D. H. Acta Cryst. C, 1999, 55, 1402.

“The square pyramidal Pd(II) complex of a cross-bridged tetraazamacrocycle” Hubin, T. J.; Alcock, N. W.; Busch, D. H. Acta Cryst. C, 1999, 55, 1404.

“Template control of supramolecular architecture” Hubin, T. J.; Kolchinski, A. G.; Vance, A. L.; Busch, D. H. in Advances in Supramolecular Chemistry; Gokel, G. W., Ed.; JAI Press Inc.: Stamford, CT, USA, 1999, Vol. 5, p. 237.

“Synthesis and X-ray crystal structure determination of the first transition metal complexes of the tetracycles formed by tetraazamacrocycle-glyoxal condensation: PdL*Cl2” Hubin, T. J.; McCormick, J. M.; Alcock, N. W.; Busch, D. H. Inorg. Chem., 1998, 37, 6549.

“Ultra rigid cross-bridged tetraazamacrocycles as ligands--the challenge and the solution” Hubin, T. J.; McCormick, J. M.; Collinson, S. R.; Alcock, N. W.; Busch, D. H. J. Chem. Soc., Chem. Commun., 1998, 1675.